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宾州大学对哈萨克斯坦人类基因历史与蒙古扩张的研究

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发表于 2012-8-30 19:12:52 | 显示全部楼层 |阅读模式
Penn Anthropologists Delve Into Genetic History of Kazakhstan and the Mongolian Expansion 宾州大学对哈萨克斯坦人类基因历史与蒙古扩张的研究

[Нийтэлсэн: 11:20 26.04.2011 ]
www.media-newswire.com

Researchers at the University of Pennsylvania have painted the clearest picture yet of the history of the Kazakhs of the Altai Mountain Range, providing insights into the heritage of a wide swath of people in Central and East Asia. Using genetic techniques, Theodore Schurr and doctoral student Matthew Dulik, both of the Penn Department of Anthropology, worked with Ludmila Osipova from the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk.
Schurr’s team’s research was published in the open access journal PLoS One. These findings are a continuation of work that Schurr and colleagues have been conducting in the Altai region for a decade.

“It’s a key area because it’s been a crossroads and conduit for people for thousands and thousands of years,” Schurr said. “People not only moved out of it to settle much of Siberia and probably did so more than one time, but it is also possibly the ancestral homeland of Native Americans.”

Future research by Schurr and his team will attempt to trace the movement of these lineages as they crossed the Bering Strait into North America.

While this study examines the paternally inherited Y-chromosomes of self-identified Kazakhs in Russia’s Altai Republic, the researchers previously published a similar study looking at ancestral lineages in the region using mitochondrial DNA, which is maternally inherited. Adding the male dimension to the historical picture of Altai Kazakhs was especially important, however, given the role that the 13th-century expansion of the Mongol Empire played in the formation of ethnic Kazakhs.

“The sweep of people coming in from Mongolia was largely male,” Schurr said. “They left their imprint on much of Central Asia, including Kazakh populations, and we’re able to see that more clearly with paternal lineages than maternal ones.”

Because women do not have Y-chromosomes, sons receive all of the genetic information contained within them directly from their fathers. These paternal lineages can be used to extrapolate male connections through many generations of fathers and sons.

Testing modern populations for certain Y-chromosome markers can determine the paternal lineages to which present-day men belong. Combining that genetic data with archeological, linguistic and climatological findings allowed the researchers to map Kazakh population groups within time and geographic space.

While some of these lineages can be traced thousands of years into the past, the most significant influence on both Altai Kazakhs and their countrymen to the west occurred within the last eight centuries, during the Mongol expansion.

“There are a couple of lineages associated with the Mongol expansion, including one called C3*, which is specifically associated with Genghis Khan and his male relatives,” Schurr said. “Where we see that lineage, we see the influence of Mongol men and can reconstruct the westward Mongol expansion. We’d expect to see that the newest mutations are the farthest west and the oldest ones are in the Mongol homeland, which they in fact are.”

This archeogenetic analysis also allowed the researchers to examine the genetic influence that indigenous Altai populations had on other groups and, as result, inform the kind of nomadic lifestyle they practiced.

“We use the same techniques to analyze the Altai lineages themselves and determine whether they were brought in from elsewhere or expanded from their source area into places north, west and east,” Schurr said. “We can see these connections throughout much of Siberia because it’s a very dynamic area, and, even though they live in small groups, they are moving around a great deal.”

The Altai region lies near the ancient Asian network of trade routes known as the Silk Road. It served as an important connection for trade routes to the north, into Siberia. In addition commercial goods, the Silk Road moved people across the whole of the continent and beyond.

This study was supported by the University of Pennsylvania, the National Science Foundation, the Social Sciences and Humanities Research Council of Canada and the Russian Basic Fund for Research. National Geographic Society also provided infrastructural support to the Schurr lab.
发表于 2012-8-30 19:57:24 | 显示全部楼层
在美国宾夕法尼亚大学的研究人员描绘的历史哈萨克的阿尔泰山脉最清晰的画面,一个广袤的中亚和东亚人的遗产提供的见解。利用基因技术,西奥多·舒尔博士的学生马修Dulik,都宾夕法尼亚大学人类学系,曾与卢德米拉奥西波娃从细胞学和遗传学研究所,科学,新西伯利亚,俄罗斯科学院西伯利亚分院。
舒尔的团队的研究结果发表在开放存取期刊PLoS一个。这些结果是继续开展工作,舒尔和他的同事已经在阿尔泰地区进行了十年。

舒尔说:“这是一个关键的领域,因为它是一个十字路口,管道成千上万年的人,”。 “人们不仅搬出它解决许多西伯利亚和可能超过一次这样做,但它也可能是土著美国人的故乡。”

舒尔和他的团队未来的研究将试图跟踪这些血统的运动,因为他们越过白令海峡进入北美。

虽然这项研究考察了父系遗传的Y染色体的自我认定的哈萨克人在俄罗斯的阿尔泰共和国,研究人员发表了类似的研究在该地区的远祖世系,这是母系遗传的线粒体DNA。阿尔泰哈萨克人的历史画卷将男性的尺寸是特别重要的,但考虑到13世纪的蒙古帝国的扩张起到的作用,在形成哈萨克族。

“扫从蒙古来的人,大部分为男性,舒尔说。” “他们留下了他们的印记,中亚许多地区,包括哈萨克族人口,我们可以更清楚地看到,与父亲比母亲的血统。”

因为女性没有Y染色体,的儿子收到所有的遗传信息包含在其中,直接从他们的父亲。父亲的血统可以用来推断男性的连接,通过几代人的父亲和儿子。

测试特定的Y染色体标记的现代人群可以决定当今男子属于父系血统。相结合的遗传资料与考古,语言和气候的研究结果使研究人员能够在时间和地理空间映射哈萨克族人口群体。

虽然这些谱系可以追溯到数千年前的过去,最显着的影响到西部的阿尔泰哈萨克和他们的同胞在过去八个世纪,在蒙古发生。

“有一对夫妇宗族与蒙古,其中包括所谓的C3 *,这是专门与成吉思汗和他的男性亲属,”舒尔说。 “如果我们看到的血统,我们看到蒙古男人的影响,可以重建向西蒙古人的扩展。我们希望看到最新的突变是最遥远的西部和蒙古人的家园,他们其实是最古老的。“

这也让archeogenetic分析的研究人员,研究土著阿尔泰种群的遗传因素的影响,对其他团体和,结果,告知他们实行的那种游牧的生活方式。

“舒尔说:”我们使用相同的技术来分析自己的阿尔泰血统,并确定他们是否带来了从其他地方或从他们的源区扩大到地北,西,东,。 “我们可以看到这些连接整个西伯利亚,因为它是一个非常有活力的地区,而且,即使他们生活在小群体,他们正在围绕一个很大。”

阿勒泰地区位于靠近古老的亚洲网络,被称为“丝绸之路”的贸易路线。它作为一个重要的贸易路线连接到北部,进入西伯利亚。除了商业产品,丝绸之路​​移动在整个大陆及以后的人。

这项研究是由美国宾夕法尼亚大学,美国国家科学基金会,社会科学和人文研究理事会,加拿大和俄罗斯基础研究基金的支持。美国国家地理学会提供基础设施支持的舒尔实验室。
发表于 2012-8-30 19:57:46 | 显示全部楼层
谷歌翻译机,谢谢谷歌
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